Hydroxyl radical generation from heart mitochondria damaged by ischemia.
نویسنده
چکیده
The hydroxyl radicals are known to be a biologically active oxygen species. A remarkable enhancement of hydroxyl radical generation was observed in the mitochondria obtained from ischemic myocardium. The hydroxyl radicals are the primary reactive species leading to cellular damages, such as membrane damages, DNA damages, enzyme inactivation, protein denaturation and so forth. The origin of the hydroxyl radicals appeared in mitochondria was discussed.
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ورودعنوان ژورنال:
- Journal of nutritional science and vitaminology
دوره Spec No شماره
صفحات -
تاریخ انتشار 1992